Liver-specific Overexpression of Scavenger Receptor BI Decreases Levels of Very Low Density Lipoprotein ApoB, Low Density Lipoprotein ApoB, and High Density Lipoprotein in Transgenic Mice
نویسندگان
چکیده
منابع مشابه
Low-Density Lipoprotein: Structure, Dynamics and Lipid –ApoB-100 Interactions
The simulated lipid droplet contained 630 1-palmitoyl-2-oleoyl-3-phosphatidylcholine (POPC), 80 1-palmitoyl-3-phosphatidylcholine (denoted as lysoPC in the main article), 600 cholesterol (CHOL), 1600 cholesteryl oleate (CO), and 180 trioleate (TO) molecules. This molecular composition is similar to the average physiological composition seen in experiments [17]. The lipid droplet was constructed...
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background: the association between the lipid profiles level and the incidence and severity of coronary heart disease (chd) is very pronounced in epidemiological studies, and an inverse relation between physical fitness and the incidence of coronary heart disease has been observed in many studies. the aim of this study was to investigate the impact of a soccer match on lipid parameters of profe...
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To study the role of apoC1 in lipoprotein metabolism, we have generated transgenic mice expressing the human APOC1 gene. On a sucrose-rich diet, male transgenic mice with high APOC1 expression in the liver showed elevated levels of serum cholesterol and triglyceride compared with control mice (5.7 6 0.7 and 3.3 6 2.1 vs. 2.7 6 0.1 and 0.4 6 0.1 mmol/liter, respectively). These elevated levels w...
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This manuscript was presented in part at the 31st Annual Meeting of the Council on Arteriosclerosis, American Society for the Study of Arteriosclerosis, American Heart Association. 1977. Circulation. 56(Suppl. III): 22. (Abstr.) Received for publication 2 December 1977 and in revised form 9 February 1978. and apoC) contained by negative staining, many disklike structures. The study demonstrated...
متن کاملVery Low Density Lipoprotein (VLDL)
Triglyceride (TG) or more accurately triacylglycerol is simply a compound of three acyl groups (fatty acids) attached to a glycerol molecule. They are easily measured in the laboratory and reported as serum TG level: it actually refers to all of the TG that are being trafficked within all of the lipoproteins that exist in a deciliter of plasma. A physiologic fasting TG concentration is on avera...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1998
ISSN: 0021-9258
DOI: 10.1074/jbc.273.49.32920